Until recently V10s had rarely been a popular configuration for road cars: a V12 is only slightly more complicated and runs more smoothly and a V8 is less complex and more economical.
* Dodge developed a V10 version of its LA series small block for use in trucks. However, the engine saw its first production use in substantially revised form in the Dodge Viper. The original truck version of the engine was eventually used starting in 1994 in the Dodge Ram.
* The Dodge Viper engine uses a 8.3 L (8.0 L in the previous generation) V10 engine, which has since been made available in the Dodge Ram SRT-10 Ram sport pickup. It is a 90 degree V10, but is arranged in an odd-firing order to allow for smooth operation without a balance shaft. The 2006 production 8.3 L engine is rated 510hp 535lbft. Highly modified naturally aspirated variants have run to 750 hp, and turbocharged variants to over 1200 hp.
* Bristol has utilized the 8.0L Viper V10 crate engines in their cars, one tuned to 525 hp is used in the Bristol Fighter. The 2004 Bristol S model is tuned to 628 hp.
* The Ford Triton V10 was developed as a replacement for Ford's aging 460 big block. The engine is a member of the Ford Modular engine family, which eliminates the need for Ford to maintain separate big-block and small-block families. The engine is available in the F250 and F-350 pickup trucks and the Ford Excursion full size SUV, as well as the E-Series full-size van.
* The Volkswagen Phaeton and Volkswagen Touareg currently have a 5.0 L turbocharged Diesel V10 option, available in Europe, making them the first diesel V10-powered sedan and SUV. They are rated 313 PS (230 kW).
* BMW has introduced a 5.0 L V10 in the 2005 BMW M5, marking the first non-Diesel V10 sedan. It reaches a maximum power of 507 PS (373 kW).
* The Lamborghini Gallardo also has a 90 degree 5.0 L DOHC V10 engine. It is has recently been improved to 520 PS (383 kW). A bigger (5.2 L) version of the engine, detuned to 450 PS (331 kW) version of the engine, is used in 2006 Audi S8.
* Porsche has introduced the Carrera GT with a 68 degree V10 displacing 5.7 L and producing 612 PS (450 kW).
